Research Engineer 3 (Modeling)

Oregon Health & Science UniversityOregon Health & Science University

Portland, OR, US
Job Description

Department Overview

Overview: The Cancer Early Detection Advanced Research (CEDAR) center is a collaborative institution within the OHSU Knight Cancer Institute. The Knight Cancer Institute, known as one of the pioneers in personalized cancer medicine, is an international leader in research and cancer treatment. At CEDAR our mission is to detect and stop lethal cancers at the earliest stage because early detection saves lives. This is an ambitious goal, one that requires novelty, creativity, and innovation. We are comprised of biologists, chemists, biomedical engineers, computationalists, and clinicians conducting groundbreaking translational cancer research to help people maintain a high quality of life and reduce cancer mortality, to create a global early detection community, and to have a positive impact on the Oregon economy.


Our Commitment to Diversity: CEDAR is committed to increasing the diversity of the campus community. We are dedicated to promoting inclusion and multiculturalism by having outstanding researchers of diverse backgrounds work together on multiple projects. We encourage high-risk, high-reward research projects because defeating cancer requires out-of-the-box thinking and new perspectives. Our research is milestone driven to ensure that each project is fulfilling its stated goals.


Every Knight Cancer employee is expected to embody our guiding principles:

  • We act BOLDLY—Breakthroughs require pushing the boundaries of science, exploring new frontiers, and thinking differently
  • We SUPPORT each other—Respect leads to trust, which leads to excellence
  • We work as a CONNECTED team—We must leverage our collective brain power to conquer cancer because no one individual can do it alone

Function/Duties of Position

CEDAR is currently looking for a Research Engineer 3 with experience and expertise in the areas of:

  • Computational biophysicist, including molecular modeling and simulations of biomolecules to predict structure, interactions and dynamics of proteins, nucleic acids
  • Molecular docking, Free energy calculations, and advanced sampling methods, including Umbrella sampling, Replica exchange molecular dynamics
  • High performance computing on clusters using slurm, scripting/coding with bash, python, R and similar environments 


As a Research Engineer, you will be part of collaborative project teams focused on enabling technologies to improve biomarker identification, characterization and quantifications to advance early cancer detection. Under occasional supervision, you will use your training and experience to design, develop, deploy, support, and integrate technologies for cancer early detection. We expect the candidates to collaborate tightly with multiple ongoing large team science projects programs. You will maintain a high level of professional expertise in the field, work under minimal supervision to generate research data and establish analysis pipelines. You will also contribute to technical writing and presentations when necessary.


Duties Include:

  • Independently develop and manage research experiments, determining the most suitable methods to be used.
  • Interpret and perform complex data analysis on experimental results and determine whether they are consistent with goals. 
  • Collect, record, organize, and verify the accuracy of data; keep detailed and accurate laboratory records; tabulate data, perform calculations, prepare charts, graphs and reports.

Required Qualifications

  • Master's Degree in relevant field AND 3 years of relevant experience OR Bachelor's Degree in relevant field AND 5 years of relevant experience
  • Those with Bachelor's in relevant field AND 3 years of relevant experience will be considered at the Research Engineer 2 level
  • Experience in modeling and simulations of soft matter/biological systems
  • Molecular dynamics and Monte Carlo simulations
  • Free energy calculations, and advanced sampling methods
  • Excellent communication, analytical and organizational skills
  • Ability to work independently and as part of a team while being collaborative in resolving problems
  • Ability to assist in proposal writing for extramural funding as part of a collaborative effort
  • Ability to prioritize multiple tasks at one time
  • Must possess energy and drive to coordinate multiple projects simultaneously
  • Ability to use tact and diplomacy to maintain effective working relationships

Additional Details

Apply online. Please be sure to upload a Cover Letter and Resume/CV.

Effective Oct. 18, 2021, all OHSU employees were required to be fully vaccinated against COVID-19 unless they had an approved medical or religious exception. If you are hired by OHSU, you will need to provide proof of vaccination (or approved exception) within 10 days of starting work.

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All are welcome

Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or As an organization devoted to the health and well-being of people in Oregon and beyond, OHSU requires its employees to be fully vaccinated against COVID-19.
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