Bioinformatician I (Dr. Vabret's Lab) - Immunobiology Center

The Mount Sinai HospitalThe Mount Sinai Hospital

New York, New York
Job Description

Strength Through Diversity

Ground breaking science. Advancing medicine. Healing made personal.


We have an immediate opening for a Bioinformatician I in Transcriptomics, Proteomics and Immunotherapy development.


The Vabret laboratory (Icahn School of Medicine at Mount Sinai in NYC) is looking for a motivated, innovation-focused scientist to join our computational team. As part of a multi-disciplinary team comprised of wet lab scientists, computational researchers and physicians, you will play a key role in developing new cancer immunotherapies. We are looking for a candidate eager to develop novel approaches to leverage unique multi-omics datasets that focus on the quantification of transposable elements and characterization of their immunogenicity. This is an opportunity to learn from immunologists and be a part of a group with a wide range of experience in computational and cellular biology.


The Bioinformatician I will be responsible for developing and running our computational analysis pipeline that integrate datasets of various nature, including: single-cell and bulk RNA sequencing, ribosomal profiling, Mass Spectrometry and antigen dataset.


Applicants should send a cover letter discussing present and future research interests as well as a CV.


Roles & Responsibilities: 

  • Conduct independent research work on key scientific questions relevant to the field of Immunotherapy.
  • Develop, manage and maintain RNAseq and mass spec analysis pipelines.
  • Curate, integrate and analyze internal and external sequencing data.
  • Collaborate with computational and biological team members to address needs of laboratory research. Assist collaborators with data analysis, and interpretation.
  • Present in meetings, prepare and submit publications of scientific findings.
  • May be involved in sequence and structural analysis, data mining, or statistical modeling.
  • Identifies and resolves technical issues and proposes upgrades to current software.
  • Other related duties as assigned.



  • Education: B.S. in computational biology, bioinformatics, computer science, or similar. M.S. preferred
  • Experience: 3 years’ experience required
  • Working experience with genetics or statistics analysis software and online resources. Experience in programming environments such as Matlab, R statistical package, BioConductor, Perl or C++.
  • Prior experience working with genomic or proteomic sequence data, analyzing biological datasets, or developing computational workflows
  • Strong scientific programming skills. Preferably in Python, R or other equivalent language.
  • Attention to detail, documentation, organizational, and problem-solving skills.
  • Team-oriented.
  • Experience with pipeline development and management is a plus.


Strength Through Diversity


The Mount Sinai Health System believes that diversity, equity and inclusion are drivers for excellence. We share a common devotion to delivering exceptional patient care. Yet we’re as diverse as the city we call home- culturally, ethically, in outlook and lifestyle. When you join us, you become a part of Mount Sinai’s unrivaled record of achievement, education, and advancement as we revolutionize medicine together and participate actively as a leader within the Mount Sinai Health System by:


  • Serving as the primary resource management representative of the Mount Sinai leadership teams, committees, etc., and acting as the primary executive leader interface between Mount Sinai and key executives from the health systems’ vendors and partners.


  • Engaging with relevant thought leaders and policy-makers at the federal and state levels, and representing the Health System as assigned.


  • Using a lens of equity in establishing and promoting policies and procedures and providing opportunities for all to thrive.


  • Confronting racist, sexist or other inappropriate behavior and challenges exclusionary organizational practices and serving as a role model to promote anti-racist behaviors.


  • Inspiring and fostering an environment of anti-racist behaviors among and between departments and co-workers.


We work hard to acquire and retain the best people, and to create a welcoming, nurturing work environment where you can develop professionally. We share the belief that all employees, regardless of job title or expertise, can make an impact on quality patient care.


Explore more about this opportunity and how you can help us write a new chapter in our story!


Who We Are


Over 42,000 employees strong, the mission of the Mount Sinai Health System is to provide compassionate patient care with seamless coordination and to advance medicine through unrivaled education, research, and outreach in the many diverse communities we serve.


Formed in September 2013, The Mount Sinai Health System combines the excellence of the Icahn School of Medicine at Mount Sinai with seven premier hospital campuses, including Mount Sinai Beth Israel, Mount Sinai Beth Israel Brooklyn, The Mount Sinai Hospital, Mount Sinai Queens, Mount Sinai West (formerly Mount Sinai Roosevelt), Mount Sinai Morningside (formerly Mount Sinai St. Luke’s), and New York Eye and Ear Infirmary of Mount Sinai.


The Mount Sinai Health System is an equal opportunity employer. We comply with applicable Federal civil rights laws and does not discriminate, exclude, or treat people differently on the basis of race, color, national origin, age, religion, disability, sex, sexual orientation, gender identity, or gender expression.


EOE Minorities/Women/Disabled/Veterans


The Mount Sinai Health System (MSHS) provides a salary range to comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $58,661.00 - $82,400.00 Annually. Actual salaries depend on a variety of factors, including experience, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.

Jobs from the Organisation